TL;DR
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Vytrus Biotech says it has quantified two forms of plant-derived PDRN in its hair-care actives, extending its plant PDRN portfolio across skin, scalp and hair. The company cites product-specific clinical and ex vivo findings, but the supplied report does not provide study sizes, full methods or independent verification.
Vytrus Biotech says it has quantified two forms of plant-derived PDRN in its hair-care actives, extending its portfolio of ingredients for skin, scalp and hair. The company also reports product-specific findings on hair loss, scalp redness and curly-hair performance, though the available report does not include study sizes or full methods.
Vytrus describes its approach as combining Phyto-PDRN, DNA fragments that act at the cell surface, with ExoPDRN, which the company says is naturally encapsulated in plant exosomes. It presents the two forms as a complementary strategy acting at the cell surface and inside cells. The report does not provide the underlying measurements or explain how the quantities were determined.
For hair care, Vytrus says it has quantified both forms in its actives for the first time. It links Capilia Longa, derived from Curcuma longa stem cells, to reduced hair loss and increased hair density, describing those outcomes as clinically proven. The company says scientific literature associating PDRN with hair growth is consistent with the product’s reported benefits; the supplied material does not identify the studies or provide their results in detail.
Vytrus also reports that Elaya Renova, made from Mediterranean olive stem cells, reduced scalp redness versus placebo in a study, which the company says supports a healthy scalp environment, a focus shared by skin-care products for sensitive skin. A separate new ex vivo curly-hair study found that one leave-on application improved hydration, reduced combing effort and frizz, including under high humidity, and increased curl definition, outcomes also sought with curly-hair care products. Ex vivo findings are generated outside a living person, so they do not by themselves establish the same effects in everyday use.
A Wider Plant PDRN Hair Portfolio
The report matters to cosmetic formulators because it presents plant-derived PDRN as an ingredient platform spanning skin, scalp and hair rather than a skin-care-only proposition. Vytrus says its portfolio now includes products aimed at skin regeneration and soothing, hair-loss prevention and density, scalp comfort, and curly-hair care. That gives product developers several potential applications to evaluate, but does not establish that the ingredients will produce the same outcomes across different formulations or users.
For consumers, the distinction between company-reported product studies and broad claims about PDRN is important. The report provides specific outcomes for named ingredients, but not enough information to judge evidence quality, effect size or how long any results last. The findings are therefore an update on ingredient development, not independent confirmation that plant PDRN products treat hair loss or skin conditions.
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From Skin Studies to Hair Care
The supplied report says these hair-care findings build on plant-based PDRN studies Vytrus presented in April for skin care; it does not specify the year. In that work, the company described Centella Reversa as combining Phyto-PDRN and ExoPDRN in its secretome for skin rejuvenation, regeneration and cellular DNA protection. It described Sensia Carota as containing Phyto-PDRN and being designed to calm and protect sensitive skin while reducing redness.
The new hair-related claims add to that earlier skin portfolio. The source article is a report about Vytrus’ ingredients and research, not a published independent trial or regulatory assessment. Its descriptions of clinical and ex vivo findings should be read as claims attributed to the company unless supported by the underlying study documentation.
““For the first time, Vytrus has quantified Phyto-PDRN and ExoPDRN in its hair care actives.””
— Vytrus Biotech, as described in the Cosmetics Business report
Study Details Still Missing
The report does not give sample sizes, study durations, participant characteristics or full protocols for the cited clinical findings. It also does not name the placebo-controlled scalp study, quantify the change in redness, or state whether the reported hair-loss and density outcomes were measured against a control group. The underlying data and any peer-reviewed publications are not included in the supplied material.
For the curly-hair results, the source identifies the work as ex vivo and describes a single application, but does not specify the sample count, measurement methods or whether the results have been replicated in people using the product. The report also does not clarify how PDRN quantities were measured or independently validated. These gaps limit comparisons between products and make it difficult to assess how well lab or clinical findings translate to routine use.
Underlying Evidence to Watch
The next useful information would be publication or release of the study methods and data, including participant numbers, controls, measurement results and the duration of observed effects. Details on the quantification method for Phyto-PDRN and ExoPDRN would also help formulators assess the ingredient claims and compare them with other materials.
Vytrus says formulators can contact the company for further information. The supplied report does not announce a product launch date, a regulatory decision or a new independent study, so those developments remain unconfirmed.
Key Questions
What did Vytrus report about plant PDRN?
Vytrus says it quantified Phyto-PDRN and ExoPDRN in its hair-care actives for the first time and reported findings for products aimed at scalp, hair and skin care.
What is the difference between Phyto-PDRN and ExoPDRN?
In Vytrus’ description, Phyto-PDRN consists of DNA fragments that act at the cell surface, while ExoPDRN is PDRN naturally encapsulated within plant exosomes. The report does not provide independent evidence assessing this proposed distinction.
What hair-care results did the report describe?
The company says Capilia Longa is clinically proven to reduce hair loss and increase density. It also reports reduced scalp redness for Elaya Renova versus placebo, and ex vivo improvements in curly-hair hydration, combing effort, frizz and curl definition after one leave-on application.
Are the reported results independently verified?
The supplied report does not include the underlying study papers, full methods or independent verification. It attributes the findings to Vytrus, and the curly-hair results are identified as ex vivo rather than a trial of routine use in people.
Source: cosmeticsbusiness.com
